J Med Life Sci > Volume 11(2); 2014 > Article
Journal of Medicine and Life Science 2014;11(2):174-178.
DOI: https://doi.org/10.22730/jmls.2014.11.2.174    Published online December 18, 2018.
내장지방 및 피하지방 면적과 인슐린 민감성 지표들과의 상관관계
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Relation between visceral & subcutaneous abdominal fat area and insulin sensitivity indices
Ji Hyon Kim, Ji Hyeon Moon, Hyeon Ju Kim, Mi Hee Kong
Abstract
Obesity is associated with complications such as hyperlipidemia, hyperinsulinemia, hypertension and cardiovascular diseases. We studied the relation of visceral & subcutaneous abdominal fat area and insulin sensitivity indices in nondiabetics Korean adults. This is a cross-sectional study by 204 patients who visited a Health Promotion Center of one hospital. We analyzed the association of anthropometry(waist circumference, BMI), visceral & subcutaneous fat by abdominal fat CT, insulin sensitivity or resistance indices(HOMA-IR, QUICKI, 1/insulin, Glucose/insulin), and plasma concentrations of lipid profiles. We found that in men, VFA and VSR have a negative correlation with Insulin sensitivity indices(QUICKI, 1/fasting insulin, G/I ratio) and a positive correlation with cholesterol and HOMA-IR. In women, we found that VFA and VSR have a negative correlation with HDL-cholesterol and QUICKI and positive correlation with triglyceride and HOMA-IR. After adjusted for age, BMI and waist circumference, we found that only in men, VFA and VSR have a negative correlation with Insulin sensitivity index(QUICKI, 1/fasting insulin, G/I ratio). As shown above, in men, Visceral fat & visceral fat/subcutaneous fat ratio are related strongly to Insulin resistance and sensitiviyt index.
Key Words: Visceral fat, Subcutaneous fat, Metabolic Syndrome, Insulin Resistance
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