| 약물에 의한 심혈관계 부작용 |
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| Drug-induced cardiovascular disorders |
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Eunkyoung Lee, Jaechun Lee, HyeJung Han |
Correspondence:
Jaechun Lee,
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| Abstract |
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Adverse drug reactions (ADRs) affecting cardiovascular system might be underestimated and underreported in clinical
practice. Most common culprit drugs are anthracyclines, antipsychotics and cyclooxygenase (COX)-2 inhibitors. Anthracyclines
may induce myocardial damage with oxidative stress, which is mostly irreversible. Type I ADRs are commonly encountered in
antipsychotic use. Attention should be paid to the risk of sudden cardiac death related to some antipsychotics. COX inhibitors
pharmacologically have antithrombotic activities. However, in COX2 selective inhibitors, myocardial infarction and stroke might be
induced paradoxically. |
| Key Words:
Adverse drug reaction, Cardiovascular system, Cardiovascular diseases |
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