J Med Life Sci > Volume 12(2); 2015 > Article
Journal of Medicine and Life Science 2015;12(2):37-38.
DOI: https://doi.org/10.22730/jmls.2015.12.2.37    Published online December 18, 2018.
Bilateral striopallidodentate calcinosis in a patient with myasthenia gravis
Ji-Yong Shin, Sa-Yoon Kang
Correspondence:  Sa-Yoon Kang,
Bilateral symmetric calcification involing striatum, pallidum with or without deposit in dentate nucleus is reported from asymptomatic individuals to a variety of neurological conditions. Clinically it may present with an array of movement disorders, dementia, cerebellar impairment and speech disorder. We report a myasthenia gravis patient with dysarthria which did not respond to pyridostigmin. Brain MRI showed bilateral striopallidodentate calcinosis (BSPDC). To our knowledge, there is no reported case having anti-acetylcholine receptor antibody and massive intracranial calcifications. This case indicates that BSPDC may develop in diverse neurological disorders.
Key Words: Anti-acetylcholine Receptor Antibody, Calcification, Myasthenia Gravis, MRI

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