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Drug allergy |
Jaechun Lee |
Correspondence:
Jaechun Lee, |
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Abstract |
Drug allergy is defined as the adverse drug reaction provoked by immunological mechanisms or roughly “type B” reaction,
the mechanism of which cannot be explained by its own pharmacological mechanism. Drug allergy rarely happens in clinical
practice, however, is usually dose-independent, unpredictable, and relatively severe in clinical manifestations. To find the safe
alternatives and to prevent further reactions, the causative agents should be investigated. Complete history taking of exposed
drugs and drug provocation tests are the mainstay in the diagnosis of the culprit drugs. The information of culprit drugs should
be opened and shared among healthcare providers for the further drug safety, called as pharmacovigilance. |
Key Words:
Drug hypersensitivity, Allergy, Drug eruptions, Pharmacovigilance |
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