J Med Life Sci > Volume 9(2); 2012 > Article
Journal of Medicine and Life Science 2012;9(2):123-127.
DOI: https://doi.org/10.22730/jmls.2012.9.2.123    Published online December 31, 2012.
Definition and Prevalence of Salt Sensitivity and Salt-sensitive Hypertension
Seung-Jae Joo
Department of Internal Medicine, Jeju National University School of Medicine, Jeju, Korea
Correspondence:  Seung-Jae Joo, Email: sejjoo@jejunu.ac.kr
Received: 7 December 2012   • Revised: 14 December 2012   • Accepted: 21 December 2012
Abstract
High salt intake is associated with significantly increased risk of stroke and total cardiovascular disease. Reduction in habitual dietary salt intake of 6 g/day decreases systolic and diastolic BP, but not in all hypertensive subjects. Salt sensitivity is defined as the tendency for BP to fall during dietary salt restriction and rise during salt supplementation. Salt sensitivity is diagnosed by a low and high salt diet protocol or a rapid sodium, volume expansion and contraction protocol. Prevalence of salt sensitivity ranged from 30 to 60% in hypertensive subjects and from 15 to 46% in normotensive subjects. Salt sensitivity is more frequently found in hypertensive subjects, blacks, aged people, and women.
Key Words: Salt; Sensitivity; Hypertension; Prevalence
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