| 폐쇄성 수면 무호흡증과 고혈압 |
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주승재 |
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제주대학교 의학전문대학원 내과학교실 |
| Obstructive sleep apnea and hypertension |
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Seung-Jae Joo |
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Department of internal Medicine, Jeju National University School of Medicine, Jeju, Korea |
Correspondence:
Seung-Jae Joo, Email: sejjoo@jejunu.ac.kr
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| Abstract |
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Obstructive sleep apnea(OSA) is a common disorder of adults, which induces hypoxemia, hypercapnia, intrathoracic pressure change and arousals during the sleep. OSA may cause hypertension, angina pectoris, myocardial infarction, congestive heart failure, arrhythmia(severe bradycardia, atrioventricular block, atrial fibrillation, ventricular premature beats, and non-sustained ventricular tachycardia), and stroke through intermediary mechanisms. Recent treatment guidelines of hypertension describe OSA as one of the secondary causes of hypertension, based on the cross-sectional cohort studies and longitudinal observational studies that showed the strong relationship between OSA and hypertension. Long-term nasal continuous positive airway pressure(CPAP) decreases blood pressure of hypertensive patients with OSA. CPAP is especially effective in resistant hypertension, but its indications and clinical effectiveness are not still clear. |
| Key Words:
Obstructive sleep apnea; Hypertension; Treatment |
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