| 조영제 신독성 |
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장은희 |
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제주대학교 의학전문대학원 내과학교실 |
| Contrast-induced nephropathy |
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Eun Hee Jang |
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Department of Internal Medicine, Jeju National University School of Medicine, Jeju, Korea |
Correspondence:
Eun Hee Jang, Email: lovemd@hanmail.nel
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| Abstract |
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Contrast-induced nephropathy(CIN) is a common cause of hospital-acquired acute renal failure. Patients with chronic renal failure. diabetes mellitus， congestive heart
failure， older age，hypotension， and anemia are at particular risk. Typically. serum creatinine levels begin to increase at 48-72 hours. peak at 3 to 5 days ，and return to baseline within another 3 to 5 days. Although a variety of therapeutic interventions ， including saline hydration，diuretics，mannitol，dopamine agonist , and many other agent have been used to prevent the CIN. saline hydration is the sole efficacious therapy to protect against CIN. Recent advances have examined the effect of the antioxidant N-acetylcysteine，iso-osmolar nonionic contrast agents. hemodialysis and hemofiltration， erythropoietin to prevent the CIN. but there are many inconsistent trial results for unknown reasons. |
| Key Words:
Radiocontrast. Acute renal failure |
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