J Med Life Sci > Volume 6(4); 2009 > Article
Journal of Medicine and Life Science 2009;6(4):206-214.
DOI: https://doi.org/10.22730/jmls.2009.6.4.206    Published online September 30, 2009.
만성B형간염의 개별화 치료
송병철
제주대학교 의학전문대학원 내과학교실
Individualized therapy for chronic hepatitis B
Byung-Cheol Song
Department of Internal Medicine, Jeju National University College of Medicine, Jeju, Korea
Correspondence:  Byung-Cheol Song, Email: drsong@jeiunu.ac.kr
Abstract
The goal of anti-viral therapy in patients with chronic hepatitis B is complete suppression of HBV replication,normalization of serum alanine aminotransferase and prevention of progression of chronic liver disease to liver cirrhosis,hepatocellular carcinoma and death. For the past decade, even though the natural course of HBV infection has been well known and dramatic advances have been made in the treatment of chronic hepatitis B with the use of oral nucleos(t)ide analogue, anti-viral resistance is emerging issue in the treatment for chronic hepatitis B. Herein, I will summarize current treatment strategies to treat the patients and to prevent antiviral resistance.
Key Words: chronic hepatitis B; nucleos(t)ide analogues; resistance
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