J Med Life Sci > Volume 6(5); 2009 > Article
Journal of Medicine and Life Science 2009;6(5):365-367.
DOI: https://doi.org/10.22730/jmls.2009.6.5.365    Published online May 27, 2009.
Role of 7, 8-dihydroxyflavone on γ- ray radiation-induced reactive oxygen species production
Rui Zhang, Kyoung Ah Kang, Jin Won Hyun
Department of Biochemist, Jeju National University School of Medicine, Jeju, Korea
Correspondence:  Jin Won Hyun, Email: jinwonh@jeiunu.ac.kr
Abstract
lonizing radiation can induce oxidative stress through generation of reactive oxygen species (ROS). Flavonoids are a member of polyphenolic compounds that occur in fruits, vegetables, teas and red wines. 7, 8-dihydroxyflavone, a member of the flavonoid group, was elucidated the free radical scavenging effect against γ-ray radiation-induced ROS production. We found 7, 8-dihydroxyflavone to scavenge the intracellular ROS deleted with fluorescence spectrometer and flow cytometry.
Key Words: 7, 8-dihydroxyflavone, Reactive oxygen species, Flavonoids


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