Role of 7, 8-dihydroxyflavone on γ- ray radiation-induced reactive oxygen species production |
Rui Zhang, Kyoung Ah Kang, Jin Won Hyun |
Department of Biochemist, Jeju National University School of Medicine, Jeju, Korea |
Correspondence:
Jin Won Hyun, Email: jinwonh@jeiunu.ac.kr |
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Abstract |
lonizing radiation can induce oxidative stress through generation of reactive oxygen species (ROS). Flavonoids are a member of polyphenolic compounds that occur in fruits, vegetables, teas and red wines. 7, 8-dihydroxyflavone, a member of the flavonoid group, was elucidated the free radical scavenging effect against γ-ray radiation-induced ROS production. We found 7, 8-dihydroxyflavone to scavenge the intracellular ROS deleted with fluorescence spectrometer and flow cytometry. |
Key Words:
7, 8-dihydroxyflavone, Reactive oxygen species, Flavonoids |
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