J Med Life Sci > Volume 10(3); 2014 > Article
Journal of Medicine and Life Science 2014;10(3):205-208.
DOI: https://doi.org/10.22730/jmls.2014.10.3.205    Published online February 28, 2014.
Preliminary Results on Using Array Comparative Genomic Hybridization of Colorectal Cancer Tissues
Weon-young Chang
Department of Surgery, Jeju National University School of Medicine, Jeju, Korea
Correspondence:  Weon-young Chang, Email: orkorea@jejunu.ac.kr
Received: 21 January 2014   • Revised: 28 January 2014   • Accepted: 4 February 2014
Abstract
Recent advances in cytogenetics have provided an opportunity for improvement in the measurement of aneuploidy by comparative genomic hybridization methods. In this study, chromosomal number variation(CNV) detection for 12 human colorectal cancer DNA samples was tried. Total 82 CNV was found, 19 gains and 63 losses, which including 326 chromosomal number variation regions. These results lead us to future studies that will be required to ascertain the meaning of gains and losses of chromosomes.
Key Words: Array CGH, CNV, CNVR, Colon Cancer
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